Mesothelioma is a type of cancer that attacks the lining of the lungs, abdomen or heart. It is a devastating consequence of asbestos exposure. If you were exposed to asbestos in the workplace, even decades ago, you may be at risk of developing mesothelioma.
While the prognosis for mesothelioma can be challenging, immunotherapy offers a promising new approach to treatment. Familiarizing yourself with immunotherapy for mesothelioma can help you decide if it’s a suitable treatment for your cancer.
What is immunotherapy?
Immunotherapy harnesses the body’s natural defense system to fight cancer. Traditional chemotherapy or radiation targets all rapidly dividing cells (including healthy ones). Immunotherapy, on the other hand, helps the immune system recognize and attack cancer cells specifically. There are different types of immunotherapy, but for mesothelioma, two main categories are explored.
The first approach uses immune checkpoint inhibitors. These medications block proteins that cancer cells use to evade the immune system. By removing this “checkpoint,” the immune system can effectively target and destroy cancer cells.
The second option is a personalized approach that involves extracting T cells (immune system cells) from a patient. These T cells are then modified in a lab to help ensure they can recognize mesothelioma cells. The modified cells are then reintroduced into the body. These enhanced T cells can now actively target and eliminate cancer cells.
Immunotherapy for mesothelioma: Current status
Immunotherapy is a relatively new treatment option for mesothelioma, and research is ongoing. However, promising results have been achieved. Immune checkpoint inhibitors, like pembrolizumab (Keytruda) and nivolumab (Opdivo), have been shown to improve survival rates and manage symptoms in mesothelioma patients. CAR T-cell therapy is still in the early stages of clinical trials for mesothelioma, but it holds potential for future advancements.
Benefits and considerations of immunotherapy
Immunotherapy offers several advantages over traditional treatments. It can be less toxic than chemotherapy and radiation, leading to fewer side effects. Additionally, immunotherapy may be effective for patients who haven’t responded well to other treatments.
However, it’s important to understand that immunotherapy is not a cure for mesothelioma, and it may not be suitable for everyone. Potential side effects can include fatigue, skin rash and autoimmune reactions. It’s crucial to discuss the risks and benefits with your doctor to determine if immunotherapy is the right course of treatment for you.
While asbestos exposure carries the risk of mesothelioma, advancements in treatment offer hope. Immunotherapy presents a promising approach to managing the disease and improving patient outcomes. If you were exposed to asbestos and experienced concerning symptoms, you could also benefit from consulting a reliable legal team about compensation.